Top to bottom, that's simply an amazing roster for a 14-team league. You have a top-notch rotation that few teams will be able to match, your bullpen isn't too shabby either (dealing for Hoffman might be something to consider), and the lineup has remarkably few holes. Aramis Ramirez is still a bit iffy, and Lofton may not be a long-term solution, but otherwise the hitting is as solid as they come.
I take it this is a keeper league? If it is, your bench prospects could come in very handy as trade bait should you need an extra push toward the title. And with this team, contending for the title is definitely what you should set your sights on.