For me I have had Peavy, Preston Wilson, Chavez go down with injuries. I also have had Sheff, Zito, Millwood, Chacon suck for most of this year (though they are showing signs of life -Chacon)
Also I gave up on Finley before his sip from the foutain of youth
On the bright side I did end up drafting Graves and Casey, who I have since traded for in my mind better long term players (crawford, renteria). And i still have Alou. V-Mart was also a great pick-up.
But I'm still gonna win this $hit, BIIIIAAATCH!!