Well, to get into a discussion of "would you do X trade? would you do Y trade?" is besides the point and belonging in a different thread.
I think we can all agree that Lincecum in the 25th round is a phenomenal, fantastic value. But whether it's your best option is a different story. I see comments like the one that rjforlife makes and it confirms my belief that you can get a HELL OF A LOT for Lincecum in the 25th. He says he wouldn't trade Lincecum for Josh Hamilton and Cliff Lee. So turn that around, and imagine that if he was in your league and you had Lincecum in the 25th, it might be possible to trade Lincecum to rjforlife and not only get Hamilton and Lee, but possibly even more.
It may seem like a no-brainer when you have someone like Lincecum in the 25th, but I actually think it may even be a tougher decision deciding what to do than merely figuring out whether you'd take him as the #1 pitcher, the #3 pitcher, the #6 pitcher, and so on...Tough decision, in my opinion, and you're lucky to have it.