Sit Cuddyer, and start Hamilton.
You're also a bid outfield-heavy. I'd try to trade some of that for depth at positions at which you have no backup.
C Napoli 1B Hafner 2B Uggla 3B Upton SS Mig. Tejada
OF Juan Pierre, Sizemore, Wells UTIL Carlos Peña BN Swisher, Glaus
SP James Shields, Clemens, Lackey, Oliver Pérez, Maine, Webb, Lincecum
RP Nathan, Mo Rivera, Al Reyes