You can do a lot better than Aurilia at first base.
You'll probably eventually want Upton at third, when Lowell cools off.
you need more closers than just Valverde if you want to be competitive in saves.
Halladay, Beckett and Hudson will be solid all season long, but I have serious doubts about Suppan and Penny. Orlando Hernandez isn't worth holding on to. Neither is Yorvit Torrealba.