It really depends who you'd like to take as stupid as that sounds.
Ideally I'd like the #1 pick to take A-Rod, and I'd also fancy having the #2 to secure either A-Rod or Pujols.
I'm not so keen on picks 3-4 as I don't really want to be forced into taking Teixeira or Vlad.
Another nice scenario would be the 6th pick, which is the last easy pick of the first round before we starting mulling over Santana, Bay, Cabrera, Crawford, etc.
If it was up to be, I'd have the 1, 2, or 6 pick. With the 6th pick I'd easily take Manny (hopefully #5 takes Ortiz).
The odds of the AL MVP coming from the American League are looking pretty good.