I'll list several terrible moves, all in the same league for which I'm leading by 4.5 Games (10 Team H2H), the 2nd year with the same managers...
My worst move: Dropping David Wright for Adam Bernero when Kolb lost his job.
Other terrible moves:
Trading Dunn and Webb for Hafner after the draft.
Dropping Alou April 24th for Luis Castillo
Trading Paul Konerko for CC Sabathia May 12th
Dropping Vernon Wells on May 7th for Esteban Loaiza
Dropping Jon Garland April 25th
And yes, I'm winning this league by 4.5 Games and have won my last 6 straight weeks.
Thank you Mike Cameron, Derrick Turnbow, Chris Young, Aaron Harang, Cliff Lee, John Patterson, Milton Bradley, and my brilliant drafting