As long as he stays healthy, I would probably start Brown almost every time out. Wood is a top 10 pitcher and a K stud, so you pretty much need to start him regardless of the matchup, except maybe at Coors. Woody Williams, when he is healthy, is almost always an excellent start. In the last three years, he has given up more than 3 earned runs only 3 times, which gives you an idea of how safe he usually is. Meche might be a bit of a shaky start, because he is pretty unproven and the White Sox offense is too good not to break out in a big day one of these days. You don't want it to happen to one of your pitchers. I would let Wolf start, since the game is in Philly, at a pitcher's park and the Astros offense tends to be far less potent away from the juice box and its tiny dimensions.