I would love to be a team in your league, as there really are some different ways to approach this. If you could somehow keep your 1st rounder (6th overall) and trade your 2nd and 3rd (7th/8th) for a late 1st or high 2nd (plus and 4th or 5th) I think you might be able to maximize your return even if you lose a draft pick along the way.
At the same time I have to believe that a couple of teams built up a fantastic roster with more than five keeper-worthy players. Since it makes sense to maximize their value by getting a draft pick for it, it'll just be a matter of being the highest bidder (unless you give multiple later round picks). Despite all of that, I have to believe that at least a couple of great players will fall to the draft (even though the free market says they should all be traded for picks before the deadline).
Sorry if it's random thoughts, but there are just a lot of ways to approach this, depending on the rosters some teams have and the personalities of the owners to potentially trading with, and if any of them have an irrational man crush on one of your players that you can maximize to your trading advantage.
Short answer, I think my ideal situation would involve you keeping your first round pick and trading some combination to improve your next pick. If you have a link your league I wouldn't mind taking a quick peek.