Personally I'd keep Harden. Cliff Lee would be next choice, but Harden getting sent down to the minors for a spell doesn't concern me. He needs a little work, for sure. I'm keeping him. Too early to bail on one of the brightest young pitching prospects.
Given the A's penchant for developing nice young arms, I'd give them the benefit of the doubt over Lee at this point. I like Lee too though.
You know what you get with Ishii, and that is a terrible WHIP. I wouldn't touch him. Pavano doesn't do much for me. He is decent, but not huge upside with Pavano. Harden and Lee still have a very high ceiling for potential.
* Steroid induced record