Ben Distler says 'yes'.
http://sports.yahoo.com/fantasy/blog/ro ... tasy-73551
It's not important that you get to know Distler simply because he's won a bunch of head-to-head leagues; the interesting thing is how he wins them. He does it without home runs, RBIs, runs, and without much consideration given to batting average.
The first 11 rounds of his most recent public league draft went like this:
R1, Jake Peavy
R2, Brandon Webb
R3, CC Sabathia
R4, Dan Haren
R5, Joe Nathan
R6, Francisco Rodriguez
R7, Billy Wagner
R8, Javier Vazquez
R9, Brett Myers
R10, Trevor Hoffman
R11, Jason Isringhausen
So that's 11 pitchers in the first 11 rounds. In public leagues, you can only actually start seven on any given day.
Johan Santana was taken immediately before Peavy, which no doubt crushed Ben. He finally drafted a batter in Round 12, taking Willy Taveras. Then he took Michael Bourn in the 13th, Jerry Owens in the 14th, and Ryan Theriot in the 15th.
He didn't draft a catcher or first baseman at all. Those positions are both occupied by the same player: "--empty--."
Peavy pitched 100 non-vintage Peavy innings that year. Webb pitched 4. CC, Haren, and Javier were the 4th, 6th and 10th ranked SP's that year so he recovered a bit.