10x10 is WAY too many categories for a H2H league... There's no way I'd feel good about equating something as rare as shutouts to something as prolific as Hits or Total Bases, let alone a single player getting a CGSHO and winning you two
categories by himself that week.
As always, something gets way out of whack when you start adding too many spices into something.
With pitching categories like IP, W, CG, SHO, OUTs, QS and Ks... who the heck would even bother with fielding a closer to get some saves if they didn't have to
? There's no way a handful of Saves each week would make up for losing out on all the rest of those counting stats, and doubtful that they'd provide enough of a bump in WHIP/ERA to even notice on a weekly basis. Starting pitchers with RP eligibility would suddenly become the hottest and most sought-after players in the league, WAY
more valuable than the closers that would normally be getting fielded in those spots, if only for the IP, Ks, and OUTs they get.
I tried one of these types of leagues once... that was more than enough for me.