This league essentially rewards big bats. First basemen are your friends!!!
You're mostly going to target big power guys that don't strike out.
With your outfielders, run with your talent and pedigree, don't worry about matchups. In baseball, all things even out over time, so someone like Rasmus will not retain the value that Holliday/Ethier/Lind will, even if he has a great week. Don't overthink it.
Guillen is a great hitter too, and is hot right now, so maybe he deserves some thought... but I'd go with those three names above. (Although I haven't tracked Holliday and Lind lately. If they are slumping, swap Guillen in there. Rasmus doesn't compare to these guys imo)
As for your infield, Headley is largely unproven, and his latest value has come from SB. I'd put Derek Lee at 1st, Sandoval at 3rd.
Butler or Headley are good options for your Utility spot. Butler hits doubles, and that is rewarded in this league, so remember that. Not sure if you mentioned Stolen Bases.. but Headley would provide more value there.