I like your offense alot. I might drop Bernie Williams and Sean Casey for better OF and 1B, two positions where there is a lot of quality out there.
Your pitching needs some help. SP--Pedro is very good, Moyer is good, but will drop this yr because of age...Buehrle is a quality 3rd starter, but look for a 4th and 5th starter...For RP, Dotel is a stud, and Kolb should be OK, but plays for Brewers (yuck). Get rid of Quantrill--he is useless for fantasy baseball. I would also ditch J Seo, J Speier (not sure he will be TOR closer). Never been a big fan of O Perez as a SP, but plays in a pitcher's park and should get you 11-13 wins.