His home stats are ridiculous so far, but they've come against WAS, SDG, SFO, and LAA. I'm sitting him tonight, but I have an overabundance of 2-starts this week, so I can afford to dismiss probably 2 of my weaker matchups.
In your situation, I'd be more hard-pressed. Depends on how many SPs you're looking at for the rest of the week vs. how many your opponent's looking at. If you've got the edge on him in the amount of solid matchups for the rest of this week, then I'd sit him. If you're lagging behind considerably in that realm, then I'd also sit him. Only way I'd start him is if you think he can get the win, you think the W totals between you and your opponent will be close, and you think you'll be able to recover from the WHIP/ERA shot (look at his other SPs this week, any of them WHIP/ERA bombs waiting to happen?).