The greater question is why are you presenting such a bias toward Griffey in a fantasy league? One of the main tenets of fantasy sports is to put your biases aside as they handicap you. Not only do people KNOW that you have these preferences but you're also making decisions based on feeling, not results. Griffey is the one to drop...root for him on your own time, you're only hurting your team by keeping him on the roster.
If it's absolutely NOT going to be Griffey, then I wouldn't make a move. Wieters shouldn't be dropped, especially with Napoli your other option, and I like all your other SPers better than Hughes (at least for this season).
I agree logically with all the comments about dropping Griffey. But we all know that superstition creeps into the game of baseball. I have won the league for 3 consecutive season, although last year I went into the season taking a pass on Griffey in the draft ... I found my team in 11th place out of 12 in late June, despite being stacked with the following guys: Rollins, Howard, Soriano, Sabathia, Peavy, MCabrera, Granderson, Crawford... the list goes on. Anyway, I made a small trade for Griffey, changed the name to "Ken Griffey's Academy," the name I had used in previous years, and then went on to finish 3rd in the regular season and win it all in the playoffs.
Did Griffey's play help me win it all? Not really ... I once held onto him in late September of '06, during fantasy playoffs, when he was all but done for the year but mysteriously not on the DL. He ate up a roster spot, but the superstition kept me from dropping him then, and low and behold, I won it all that year.
Anyway, just to give a better explanation for why I have an "obligation" or at least aversion to dropping Griffey.