I'd take either end this year. Picking 1 or 2 gives me A-Rod or Pujols who I would love to build a team around. If I miss out on those two, I'm willing to risk waiting until later to get 2 studs.
Picking 10th of 12 this year I grabbed Prior and Pedro, giving me a huge K, ERA, and WHIP advantage right off the bat.
I think there are 2 top players, so ideally I'd pick 1 or 2 (A-Hole or Pujols). I think there is another 2 after them (Soriano, Helton). After they are gone, I'd prefer to pick later and hope for Prior.
I don't really want to draft Beltran, Vlad, Bonds, Manny, Maggs, Sheff, Nomar at pick 5-10. You can't pass them up, but I'd prefer getting Prior (or I'd settle for Pedro) before any of them. Beltran would be the only guy I'd really want in first round out of that group, and that would be option #7 for me. OF is too deep, and I don't want to draft a SS not named A-Rod in the first round.
This is all pre-Prior and the recurring achilles pain. Right now, I wouldn't want to draft until I find out more.
* Steroid induced record