hi rob.
depends on the type of league and the rules, etc. but here's some links to articles i like
http://www.fantasybaseballcentral.com/#1 has several good articles
also check the mock drafts on this site to see where players are generally going
the strategy i've been doing very well with this year is:
Round 1- best player available
rounds 2-4 fill in infield, assuming top studs are still on the board (ss-tejada, nomar, jeter, renteria 2b-boone, kent 3b-rolen, chavez)
after that i fill in with OF, 1B and pitchers. I'm always surprised at the quality of players still left at these postions, and there are many more sleepers there too.