Well, it does depend upon the settings # of teams/roster spots/scoring of the individual league, but if it's a standard league, it's a bad trade, but not a vetoable one. I'd say either Lackey or Penny would be the equal of Zambrano and both are more valuable than Konerko... but it's not so offensive that I'd put down the kobosh.
0-3 to 4-3. Worst choke in the history of baseball. Enough said.