I don't have serious regrets thus far, just a few second guesses. In retrospect, I would've drafted Manny Corpas in Round 9 over Trevor Hoffman in the H2H World Series while letting someone deal with B.J. Ryan past Round 15 in H2HWS California. I wonder a bit about Rickie Weeks in the two H2HWS drafts I had taken, but it was a very acceptable place to take him (9th and 10th rounds respectively). I'm not panicking about Scott Kazmir (7th rounds) in 2 of my 3 H2HWS drafts either, as I've compiled a very good staff to deal without Kazmir and I'm bullish on a quick return.
I'm content with all of my drafts so far and I'll have to knock down two more to finish drafting season.