If BJ Ryan comes back and can pitch effectively then he will be the closer, end of story. He has a huge contract, and is also flat-out better than Accardo when healthy. I would not really put Accardo in Nathan's league either.
If Ryan returns well, I could see Accardo being the set-up guy going forward at that point. League doesn't look like a guy the Jays can depend on, and Janssen still projects as a guy who should be in the rotation in future years. I don't really see any reason at all for the Jays to trade Accardo, he is one of only three guys in the bullpen right now they trust; and he is also the return the Jays got for Hillenbrand, so you can bet JP likes that too.
You've got a diamond, You've got nine men
You've got a hat and a bat, And that's not all..