well... these actually aren't homer picks, but I won two different leagues targeting these guys in 3-4
Jeter- its all about consistency (even though in real life I do not like him)
Matsui- same... power runs avg, rbis, everything but SB
Oswalt- yet again, consistently contributes greatness
Lidge/Ryan- love k's from closers, and these guys provide tons
Otherwise it depends on the league... the people who I target in an NL-only are totally different than in other leagues...