Pedro will probably not get to 300Ks but should be good for at least 250. I've had Pedro on my keeper team for the past 3 years. IMHO, he is the best pitcher out there. As long as the Sox watch his pitch count, he should be fine. He even said that he felt himself get stronger as the season went on last year and it showed.
Soriano is the best 2B out there, but do expect a drop off from last years totals. He still has horrible plate discipline, but you still can't go wrong with a 2B who missed 40-40 by 1 HR.
It will be interesting to see how Kent performs in Houston. I think Kent could easily hit 40+ bombs this year and drive in well over 110 runs, which would really challenge Soriano for who is the best 2B. Soriano's steals do give him the edge though for now.