It's funny, because the last couple of years in both fantasy baseball and football I've wound up with one of the "bookend" picks. I've grown quite accustom to it. I like it, because I can usually take a "sure" thing, and gamble with the other if I want to.
Also, the point about getting caught in runs on positions is dead on. That's the other thing I like about bookend picks: you can easily start a run by grabbing the best at a position, and, by the time it snakes back to you, you can usually grab the players you would have taken anyway. If a run has already started by the time my pick comes up, I usually will sit back and grab the best available players.